In 1931, the Bondurant brothers of Franklin County, Virginia, run a multipurpose backwoods establishment that hides their true business — bootlegging. Middle brother Forrest is the brain of the operation; older Howard is the brawn, and younger Jack, the lookout. Though the local police have taken bribes and left the brothers alone, a violent war erupts when a sadistic lawman from Chicago arrives and tries to shut down the Bondurants operation.

Reporter John Klein is plunged into a world of impossible terror and unthinkable chaos when fate draws him to a sleepy West Virginia town whose residents are being visited by a great winged shape that sows hideous nightmares and fevered visions.

Chris crashes into a carload of other young people, and the group of stranded motorists is soon lost in the woods of West Virginia, where they're hunted by three cannibalistic mountain men who are grossly disfigured by generations of inbreeding.